|
Natural Product Chemistry Division started
with the classical chemistry of screening medicinal and aromatic
plants for value added phytochemicals, new molecules and screening
of these compounds and fractions for their bioactivity. Over the
years expertise, trained manpower and state-of-the-art facilities
have been developed for specialized Research and Development in
the area of (i) herbal drugs, drug formulation and end-to-end
technology on medicinal plants (ii) isolation of bioactivity guided
extracts, fractions and new molecules (iii) standardization, quality
control and isolation of marker compounds (iv) process development
and upscaling of technologies for value added phytochemicals and
phytopharmaceuticals and chemistry of essential oil bearing plants
and their value added products.
As
per the World Bank Report, the international market for Herbal
Drugs is estimated to be more than 60 billion US$ which is expected
to grow upto 6 trillion US$ by the end of 2050. At present per
capita/year consumption of over the counter (OTC) Herbal drugs
in Germany is 37.0 US$, Europe 17.4 US$ and in India 2.8 US$,
which is likely to double in the near future. In the developing
countries, Herbal medicine still remains the mainstay of primary
healthcare because of better compatibility with human body and
lesser side effects. Moreover there has been a resurgence in the
use of Herbal Drugs in the world market. Keeping in view the status
and future trends of herbal drugs, the focus of this department
is to perform extensive R&D work on PROSPECTING BIODIVERSITY
for its chemistry to isolate phytochemicals/ phytophar- maceuticals,
activity guided extracts, fractions and single molecules for the
development standardization and quality control of herbal/synthetic
drugs and aroma chemicals.
Leads have already been obtained in our laboratory against various
diseases such as Parkinson's disease, fungal diseases, infection,
arthritis, hepatotoxicity, immune-disorders, adaptogens, asthma,
allergic disorders, cancer, diabetes and tuberculosis with or
without bioenhancers.
It
is planned to make investigation of about 200 medicinal plants
in shortest possible time. Large number of marker compounds has
been isolated from these plants, which are being used for standardizing
the active fractions from these plants. The marker compounds are
also made available to other institutes on request. Plants showing
significant bioactivities are being taken up for detailed chemical
investigation. A large number of new as well as known compounds
have been isolated, identified and their biological activity studied.
|