Regional Research Laboratory, Jammu (Council Of Scientific & Industrial Research)
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RRL
Jammu |
| Pharmacology | |||||||
| Herbal based New drug design and development
is the mandate of Pharmacology Division at Regional Research
Laboratory, Jammu. The division has four sub-sections i.e. Biopharmaceutics,
Biochemistry, Specific Pharmacology and General pharmacology.
The Biopharmaceutics has the expertise in the areas of pharmacokinetics,
pharmacodynamics and stability study. The biochemicals markers
and assays for every activity are taken up by the biochemists.
The specific pharmacology has a set of bioactivities being carried.
The active products are studied for general pharmacological
profile in the General Pharmacology laboratory.
The division of pharmacology is well equipped with modern infrastructure facilities. The plant based products (extracts/fractions/pure principles) are subjected to battery of well established in vitro as well as in vivo tests for their Biopotential, efficacy and biosafety. The spectrum of bioactivities is mainly focussed in following areas :Bioenhancer
and bioavailability The concept of bioenhancer was originally conceived by RRL, Jammu. Primary monolayer cultures of rat hepatocytes models used for screening for hepatoprotective has been successfully standardised and extended to the evaluation of bioenhancers. For the testing of hepatoprotective, antidiabetic, antiinflmmatory/ antiarthritis, immunomodulatory potential and the general pharmacological profile of the plant based products both in vivo and in vitro models are employed. Anticancer testing laboratory is fabricated with Robotics system for high throughput screening in the area. A GLP compliance animal house facility meet the day to day lab. animals requirement of experimentation. The transgenic animals facility has recently been taken up for the pharmacogenomics study. |
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